<div dir="ltr"><span style="font-size:12pt;font-family:"Times New Roman","serif"">(NOTE: Repeated Reminder with no change to contents.)<span></span></span>
<div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif""><span> </span></span></p>
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<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><b><span style="font-size:14pt;font-family:"Times New Roman","serif"">October 27,
2021</span></b><b><span style="font-size:14pt;font-family:"Times New Roman","serif""><span></span></span></b></p>
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<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><b><span style="font-size:14pt;font-family:"Times New Roman","serif"">CRISPR,</span></b><span style="font-size:14pt;font-family:"Times New Roman","serif""> part 2, presented
by Dick Wagner.<span></span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:14pt;font-family:"Times New Roman","serif"">This
week, Dick will give a brief review and then more detail. Part 1, presented
last week, can be viewed here <a href="https://www.youtube.com/watch?v=C58Ij7xy0eU" style="color:blue;text-decoration:underline" target="_blank">https://www.youtube.com/watch?v=C58Ij7xy0eU</a><span></span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:14pt;font-family:"Times New Roman","serif""><span> </span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:14pt;font-family:"Times New Roman","serif"">The
acronym “CRISPR” (Clustered Regularly Interspaced Short Palindromic Repeats)
has often been invoked when considering recent revolutionary genetic
engineering advances. This presentation will be devoted to the origin of the
term, its biological significance, and how further knowledge led to the
expansion of the meaning of this term as well as its underlying processes in
genetic engineering. Finally, the potential of CRISPR for deriving further
molecular biological information and uses from experimentation and analysis
will be discussed.<b><i><span style="font-weight:normal"><span></span></span></i></b></span></p>
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<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif""><span> </span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><b><i><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">SPECIAL NOTE - </span></i></b><i><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">Links to many of our previous sessions are
available online at <a href="http://lctg.toku.us/" style="color:blue;text-decoration:underline" target="_blank">http://lctg.toku.us/</a>,
thanks to the diligence of Steve Isenberg. This includes the space-oriented
presentations of Mars Landing from February 24, Venus Temperature from March 17,
Apollo Mission from April 14, Space Debris from May 5, Oumuamua from May 19 and
Helicopter Flight on Mars from May 26.<span></span></span></i></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:13.5pt;font-family:"Times New Roman","serif";color:black"><span> </span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">We, the Lexington
Computer and Technology Group, will meet Wednesday at the usual 10AM Eastern
Time, BUT ONLINE, using the Zoom Video Conferencing Application, facilitated by
Steve Isenberg. </span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">There is an instruction
page at <a href="https://toku.us/zoomish" style="color:blue;text-decoration:underline" target="_blank">https://toku.us/zoomish</a>
but note that the URL and phone number shown are examples.</span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif""><span> </span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">Sometime after 9:45 AM
on Wednesday, choose one of the following options:</span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></p>
<ul style="margin-bottom:0in" type="disc"><li class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">If you have the Zoom application installed, start it and join
meeting with ID 972 6146 0830</span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></li><li class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">From your browser, go to: <a href="https://zoom.us/j/97261460830" style="color:blue;text-decoration:underline" target="_blank">https://zoom.us/j/97261460830</a></span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></li><li class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">>From your smartphone, tap this: +16468769923,,97261460830</span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></li><li class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">From a “dumb” telephone, call 1 646 876 9923 and enter
meeting ID: 972 6146 0830 </span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></li></ul>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Times New Roman","serif";color:black">Once the connection is
established, you may need to locate and use the on-screen controls that turn on
the sound and the video. You should be able to see and hear others and they
should be able to see and hear you, if you have a camera and microphone (each
of which you can unmute selectively).</span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Trebuchet MS","sans-serif";color:rgb(11,83,148)">If this email wasn't addressed to you and you
would like to join the group, or if you have a friend or colleague who might
also be interested in joining, it's easy. Ask them to go to the group's
wiki page at </span><span style="font-size:12pt;font-family:"Times New Roman","serif""><a href="http://LCTG.toku.us" style="color:blue;text-decoration:underline" target="_blank"><span style="font-family:"Courier New"">http://LCTG.toku.us</span></a></span><span style="font-size:12pt;font-family:"Courier New";color:rgb(11,83,148)"> </span><span style="font-size:12pt;font-family:"Trebuchet MS","sans-serif";color:rgb(11,83,148)">and follow the simple
instructions under "Join the Email List". By being a member of
the group you'll get reminders of upcoming meetings and infrequent related
messages. No advertising. The list is tightly managed.<span></span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><span style="font-size:12pt;font-family:"Trebuchet MS","sans-serif";color:rgb(11,83,148)">Membership is free and given that all meetings
are using Zoom you only need to be connected to the Internet to join.
It's ok to join from anywhere you can get a decent Internet connection, even if
you're in orbit around Earth or on another planet or a moon (if you're
connecting from somewhere not on Earth, we'd like to chat).</span><span style="font-size:12pt;font-family:"Times New Roman","serif""><span></span></span></p>
<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><b><i><span style="font-size:16pt;font-family:"Times New Roman","serif";color:black">Below are our plans for Upcoming Meetings. For
more schedule information, please refer to <a href="https://wiki.toku.us/doku.php?id=lctg_speaker_schedule" style="color:blue;text-decoration:underline" target="_blank">https://wiki.toku.us/doku.php?id=lctg_speaker_schedule</a>
We will continue to have an online presentation (almost) every Wednesday until
it is prudent for us to resume meeting in person.<span></span></span></i></b></p>
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<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><b><span style="font-size:14pt;font-family:"Times New Roman","serif"">November 3,
2021<span></span></span></b></p>
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<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><b><span style="font-size:14pt;font-family:"Times New Roman","serif"">Fritz Haber
and Chemical Warfare,</span></b><span style="font-size:14pt;font-family:"Times New Roman","serif""> Presented by Bretislav Friederich of the
University of Berlin where he is Professor of Physical Chemistry. He is also
a highly accomplished historian of science. He has just published a chapter
in a book on the history of chemical warfare, germ warfare and other such
technologies. His article is on Fritz Haber and his role in inventing
chemical warfare during WW1. Friederich will be at Harvard for the year on
sabbatical. He is an excellent speaker.<b><span></span></b></span></p>
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<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><b><span style="font-size:14pt;font-family:"Times New Roman","serif"">November 10,
2021<span></span></span></b></p>
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<p class="MsoNormal" style="margin:0in 0in 0.0001pt;font-size:10pt;font-family:"Calibri","sans-serif""><b><span style="font-size:14pt;font-family:"Times New Roman","serif"">Potpourri,
possibly including Decoding da Vinci.</span></b><span style="font-size:14pt;font-family:"Times New Roman","serif""> This NOVA program will explain the
science behind Leonardo da Vinci’s masterpieces—and Mona Lisa’s iconic smile.<span></span></span></p>
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